BDBM604912 (R)-N-(5-Cyano-4-(3-methoxypyrrolidin-1-yl)pyridin-2-yl)-7-formyl-6-((3-carbonylmorpholino) methyl)-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide::US11667631, Example 52

SMILES CO[C@@H]1CCN(C1)c1cc(NC(=O)N2CCCc3cc(CN4CCOCC4=O)c(nc23)C(N)=O)ncc1C#N

InChI Key InChIKey=NQLPNGOXJDYXQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604912   

TargetFibroblast growth factor receptor 4(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604912((R)-N-(5-Cyano-4-(3-methoxypyrrolidin-1-yl)pyridin...)
Affinity DataIC50: 1.33nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM604912((R)-N-(5-Cyano-4-(3-methoxypyrrolidin-1-yl)pyridin...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent