BDBM604935 US11667638, Example 84

SMILES CNc1cc2[C@@H]3CNCC(C3)Cn2c(=O)c1

InChI Key InChIKey=PQACGZHZKXPWQM-GKAPJAKFSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 604935   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Bristol

US Patent
LigandPNGBDBM604935(US11667638, Example 84)
Affinity DataKi:  10.8nMAssay Description:The binding of a group of compounds mentioned above were tested for their affinity at different nAChR subtypes, specifically the α4β2, the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Bristol

US Patent
LigandPNGBDBM604935(US11667638, Example 84)
Affinity DataKi:  1.56E+4nMAssay Description:The binding of a group of compounds mentioned above were tested for their affinity at different nAChR subtypes, specifically the α4β2, the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Bristol

US Patent
LigandPNGBDBM604935(US11667638, Example 84)
Affinity DataKi:  2.75E+4nMAssay Description:The binding of a group of compounds mentioned above were tested for their affinity at different nAChR subtypes, specifically the α4β2, the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Bristol

US Patent
LigandPNGBDBM604935(US11667638, Example 84)
Affinity DataKi:  5.63E+4nMAssay Description:The binding of a group of compounds mentioned above were tested for their affinity at different nAChR subtypes, specifically the α4β2, the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent