BDBM604983 N-[3-[7-ethynyl-2- (methylamino)pyrido[2,3-d]pyrimidin- 6-yl]-4-methylphenyl]-2- (trifluoromethyl)pyridine-4- carboxamide::US11667634, Example 67

SMILES CNc1ncc2cc(c(nc2n1)C#C)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=CYGJGSGLEGETEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 604983   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM604983(US11667634, Example 67 | N-[3-[7-ethynyl-2- (methy...)
Affinity DataIC50: 10nMAssay Description:Protein kinase assay: Assay platform was used to measure kinase/inhibitor interactions as described previously (Anastassiadis et al., 2011). In brief...More data for this Ligand-Target Pair
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Date in BDB:
7/9/2023
Entry Details
US Patent