BDBM605223 US11667652, Example 18

SMILES CNc1nc(N[S@@]2(=O)=NC(=O)c3ccc4OC[C@]5(CCCc6cc(Cl)ccc56)CN(C[C@@H]5CC[C@H]5[C@@H](OC)\C=C\C[C@H](C)C2)c4c3)c2cn(C)nc2n1

InChI Key InChIKey=QWTVMHZCJKWQSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605223   

LigandPNGBDBM605223(US11667652, Example 18)
Affinity DataIC50: 0.0420nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent