BDBM605238 US11673876, Comparative Compound 1

SMILES CS(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(NCc3ccccc3)c2c1

InChI Key InChIKey=VYAONVKVKKSFER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 605238   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Mekanistic Therapeutics

US Patent
LigandPNGBDBM605238(US11673876, Comparative Compound 1)
Affinity DataIC50: 2nMAssay Description:Z′-LYTE Assay Conditions: Test Compounds: The Test Compounds are screened in 1% DMSO (final) in the well. For 10 point titrations, 3-fold seria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2023
Entry Details
US Patent

LigandPNGBDBM605238(US11673876, Comparative Compound 1)
Affinity DataIC50: 2nMAssay Description:Z′-LYTE Assay Conditions: Test Compounds: The Test Compounds are screened in 1% DMSO (final) in the well. For 10 point titrations, 3-fold seria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2023
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Mekanistic Therapeutics

US Patent
LigandPNGBDBM605238(US11673876, Comparative Compound 1)
Affinity DataIC50: 110nMAssay Description:Z′-LYTE Assay Conditions: Test Compounds: The Test Compounds are screened in 1% DMSO (final) in the well. For 10 point titrations, 3-fold seria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2023
Entry Details
US Patent