BDBM605239 US11667652, Example 35

SMILES COC(=O)c1ccc2OC[C@]3(CCCc4cc(Cl)ccc34)CN(C[C@@H]3CC[C@H]3C(O)C#CC[C@H](C)C[S@@](=O)(NC(=O)c3cn(C)nc3OC)=NC(=O)O[C@@H](C)c3ccccc3)c2c1

InChI Key InChIKey=BSEWRQZTUOKGTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605239   

LigandPNGBDBM605239(US11667652, Example 35)
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent