BDBM605268 US11667652, Example 63

SMILES COC1CCN(CCO[C@H]2\C=C\C[C@H](C)C[S@@](=O)(NC(=O)c3cn(C)nc3OC)=NC(=O)c3ccc4OC[C@]5(CCCc6cc(Cl)ccc56)CN(C[C@@H]5CC[C@@H]25)c4c3)CC1

InChI Key InChIKey=VNEMARWHBUDMTK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605268   

LigandPNGBDBM605268(US11667652, Example 63)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent