BDBM605271 US11667652, Example 66

SMILES CO[C@H]1/C=C/[C@H](O)[C@H](C)C[S@@](=O)(Nc2ncnc3nn(C)cc23)=NC(=O)c2ccc3c(c2)N(C[C@@H]2CC[C@H]21)C[C@@]1(CCCc2cc(Cl)ccc21)CO3

InChI Key InChIKey=HBLZZIUVVCDJLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605271   

LigandChemical structure of BindingDB Monomer ID 605271BDBM605271(US11667652, Example 66)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent