BDBM605281 US11667652, Example 76

SMILES COCCOCCOCCO[C@H]1\C=C\[C@H](OC)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc23)C(=O)N=[S@@](=O)(C[C@H]1C)NC(=O)c1cn(C)nc1OC

InChI Key InChIKey=ZUGICRIEDCLPEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605281   

LigandPNGBDBM605281(US11667652, Example 76)
Affinity DataIC50: 0.0480nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent