BDBM605303 US11667652, Example 98::US11667652, Example 99

SMILES COc1nn(C)cc1C(=O)N[S@@]1(=O)=NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@H]4[C@@](O)(CC(=O)N4CCOCC4)\C=C\C[C@H](C)C1)c3c2

InChI Key InChIKey=CHBBPYCZAXNRLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605303   

LigandPNGBDBM605303(US11667652, Example 98 | US11667652, Example 99)
Affinity DataIC50: 0.0310nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandPNGBDBM605303(US11667652, Example 98 | US11667652, Example 99)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent