BDBM605393 US11667652, Example 187

SMILES CO[C@H]1\C=C\C[C@H](C)C[S@@](=O)(NC(=O)NC2CC2)=NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@@H]14)c3n2

InChI Key InChIKey=BETZWDMGZCWMEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605393   

LigandPNGBDBM605393(US11667652, Example 187)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent