BDBM605460 2-(2,3- dihydrobenzo[b][1,4]dioxin- 6-yl)-6-(4-(3-hydroxy-2,2- dimethylpropylamino)piperidin- 1-yl)benzonitrile::US11673883, Example 6

SMILES CC(C)(CO)CNC1CCN(CC1)c1cccc(-c2ccc3OCCOc3c2)c1C#N

InChI Key InChIKey=MTUGNPSIGPCGTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605460   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM605460(US11673883, Example 6 | 2-(2,3- dihydrobenzo[b][1,...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent