BDBM605465 2-(2,3- dihydrobenzo[b][1,4]dioxin- 6-yl)-6-(4-((4-(4- methoxyphenyl)tetrahydro- 2H-pyran-4- yl)methylamino)piperidin- 1-yl)benzonitrile::US11673883, Example 11

SMILES COc1ccc(cc1)C1(CNC2CCN(CC2)c2cccc(-c3ccc4OCCOc4c3)c2C#N)CCOCC1

InChI Key InChIKey=HZAUOAFXLCNWEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605465   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM605465(US11673883, Example 11 | 2-(2,3- dihydrobenzo[b][1...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2023
Entry Details
US Patent