BDBM605474 2-(2,3-dihydro-1,4- benzodioxin-6-yl)-6-[4- ({[cis-2- hydroxycyclohexyl]methyl} amino)piperidin-1- yl]benzonitrile::US11673883, Example 19

SMILES OC1CCCCC1CNC1CCN(CC1)c1cccc(-c2ccc3OCCOc3c2)c1C#N

InChI Key InChIKey=YABSEKZAXYECAJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605474   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM605474(US11673883, Example 19 | 2-(2,3-dihydro-1,4- benzo...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2023
Entry Details
US Patent