BDBM605521 US11673886, Example 2

SMILES CC(C)(O)COc1ccc2c(cnn2c1C1CC1)C(=O)N[C@H]1C[C@]2(C1)C[C@@H](C2)Oc1c(sc2ccccc12)C(N)=O

InChI Key InChIKey=UFLAQOSWQKJWAJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605521   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM605521(US11673886, Example 2)
Affinity DataIC50: 20nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
US Patent