BDBM60587 3-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-1-[(4-fluorophenyl)methyl]urea (2)

SMILES O=C(NCc1ccc(F)cc1)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1

InChI Key InChIKey=IDRYNPKIMNXUCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60587   

TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Human)
Tianjin University of Science and Technology

LigandChemical structure of BindingDB Monomer ID 60587BDBM60587(3-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50: 11nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed