BDBM606131 4-[(1R)-1- aminopropyl]- 6-(dimethyl- amino)-2-{6- [(5R)-5- (fluoromethyl)- 6,7-dihydro- 5H-pyrrolo [2,1-c][1,2,4] triazol-3-yl] pyridin-2-yl}- 2,3-dihydro- 1H-pyrrolo[3,4- c]pyridin-1-one::US11684616, Example 33

SMILES CC[C@@H](N)c1nc(cc2C(=O)N(Cc12)c1cccc(n1)-c1nnc2CC[C@H](CF)n12)N(C)C

InChI Key InChIKey=BHFRZVOBWHKGQO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 606131   

LigandPNGBDBM606131(US11684616, Example 33 | 4-[(1R)-1- aminopropyl]- ...)
Affinity DataKi:  0.210nMAssay Description:PRKD2 (PKD2) and RPS6KA2 (RSK3) kinase assays were performed with Km-levels of ATP at the Thermo Fisher Scientific, Inc. (Madison, Wis.), using their...More data for this Ligand-Target Pair
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Date in BDB:
7/31/2023
Entry Details
US Patent