BDBM606137 US11684616, Example 100

SMILES CCn1cnnc1-c1cccc(n1)N1Cc2c(cc(nc2C(C)(C)N)N2CCC[C@H]2C)C1=O

InChI Key InChIKey=YEOMJKKERMIQSA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 606137   

LigandPNGBDBM606137(US11684616, Example 100)
Affinity DataKi: <0.0500nMAssay Description:PRKD2 (PKD2) and RPS6KA2 (RSK3) kinase assays were performed with Km-levels of ATP at the Thermo Fisher Scientific, Inc. (Madison, Wis.), using their...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-2(Human)
Pfizer

US Patent
LigandPNGBDBM606137(US11684616, Example 100)
Affinity DataIC50: 15.5nMAssay Description:PRKD2 (PKD2) and RPS6KA2 (RSK3) kinase assays were performed with Km-levels of ATP at the Thermo Fisher Scientific, Inc. (Madison, Wis.), using their...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase D2(Human)
Pfizer

US Patent
LigandPNGBDBM606137(US11684616, Example 100)
Affinity DataIC50: 51.2nMAssay Description:PRKD2 (PKD2) and RPS6KA2 (RSK3) kinase assays were performed with Km-levels of ATP at the Thermo Fisher Scientific, Inc. (Madison, Wis.), using their...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent