BDBM606866 US11685738, Compound A2

SMILES OC(=O)CC(CCCCCCc1ccc2CCCNc2n1)c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=ZIRQVVCLROKPMP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 606866   

TargetIntegrin alpha-V/beta-6(Human)
Ocuterra Therapeutics

US Patent
LigandPNGBDBM606866(US11685738, Compound A2)
Affinity DataIC50: 9nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent

TargetIntegrin alpha-V/beta-6(Human)
Ocuterra Therapeutics

US Patent
LigandPNGBDBM606866(US11685738, Compound A2)
Affinity DataIC50: 11.6nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent

TargetIntegrin alpha-V/beta-8(Human)
Ocuterra Therapeutics

US Patent
LigandPNGBDBM606866(US11685738, Compound A2)
Affinity DataIC50: 78.1nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent