BDBM607065 2-(5-Fluoro-2-((6-(1-methylpiperidin-4-yl)pyridazin-3-yl)amino)pyrimidin-4-yl)-7-isopropyl-3,5-dimethylthieno[3,2-c]pyridin-4(5H)-one::US11685744, Example 93

SMILES CC(C)c1cn(C)c(=O)c2c(C)c(sc12)-c1nc(Nc2ccc(nn2)C2CCN(C)CC2)ncc1F

InChI Key InChIKey=QSZSUKPGDBYGQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 607065   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM607065(US11685744, Example 93 | 2-(5-Fluoro-2-((6-(1-meth...)
Affinity DataIC50: 20nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM607065(US11685744, Example 93 | 2-(5-Fluoro-2-((6-(1-meth...)
Affinity DataIC50: 110nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK6/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent