BDBM607070 US11685744, Example 98

SMILES Cc1c(-c2nc(Nc3ccc(C4CC[N+](C)([O-])CC4)cn3)ncc2F)sc2c(C(C)C)cn(C)c(=O)c12

InChI Key InChIKey=LHNWSGDERWHZHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607070   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 607070BDBM607070(US11685744, Example 98)
Affinity DataIC50: 20nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent