BDBM607090 US11685744, Example 118

SMILES CC(C)n1c(C)nc2c(C)c(sc12)-c1nc(Nc2ccc(cn2)C2CC[C@H]3CN(C)C(=O)CN23)ncc1F

InChI Key InChIKey=FVEOQMSJTRDUFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607090   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM607090(US11685744, Example 118)
Affinity DataIC50: 20nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent