BDBM607104 US11685745, Example 37

SMILES Clc1cc2nc(CN3CCNCC3)oc2c2c1NC(=O)NC21CCCCC1

InChI Key InChIKey=VEDWYQAUJRRZGQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 607104   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)TBA

LigandBDBM607104(US11685745, Example 37)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant PDE7A1 (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
TBA
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Dart Neuroscience

US Patent

LigandBDBM607104(US11685745, Example 37)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/31/2023
Entry Details
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