BDBM607512 N-(2-bromo-6-isopropylphenyl)- 6-methyl-4-oxo-1-phenyl-1,4- dihydropyridazine-3- carboxamide::US11690850, Example 24

SMILES CC(C)c1cccc(Br)c1NC(=O)c1nn(c(C)cc1=O)-c1ccccc1

InChI Key InChIKey=SXQBZNKXGZLCDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607512   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM607512(N-(2-bromo-6-isopropylphenyl)- 6-methyl-4-oxo-1-ph...)
Affinity DataIC50: 489nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent