BDBM607514 N-(2-cyclopropyl-6- methylphenyl)-6-methyl-4-oxo- 1-phenyl-1,4-dihydropyridazine- 3-carboxamide::US11690850, Example 26

SMILES Cc1cccc(C2CC2)c1NC(=O)c1nn(c(C)cc1=O)-c1ccccc1

InChI Key InChIKey=OCYOPEJRJMIJLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607514   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM607514(N-(2-cyclopropyl-6- methylphenyl)-6-methyl-4-oxo- ...)
Affinity DataIC50: 668nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent