BDBM607534 US11690850, Example 48

SMILES Cc1cc(=O)c(nn1-c1ccccc1)C(=O)NC1CCc2cc(F)cc(F)c2NC1=O

InChI Key InChIKey=RNQSZQNMOHZSMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607534   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM607534(US11690850, Example 48)
Affinity DataIC50: 51nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent