BDBM607591 5-ethynyl-N-(3,3,3-trifluoro-2-((3-methyl-4-(3-oxomorpholino)phenyl)carbamoyl)propyl)thiophene-2-carboxamide::US11691960, Example WO2006/034822

SMILES Cc1cc(NC(=O)C(CNC(=O)c2ccc(s2)C#C)C(F)(F)F)ccc1N1CCOCC1=O

InChI Key InChIKey=KPWOVCKCEZLAIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607591   

TargetCoagulation factor X(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM607591(US11691960, Example WO2006/034822 | 5-ethynyl-N-(3...)
Affinity DataIC50: 48nMAssay Description:Measurement of active human Factor Xa using a specific chromogenic substrate which is labeled with a p-nitro-anilino group (pNA). The cleavage in bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent