BDBM607992 US11691963, Example I-150

SMILES CO[C@H]1C[C@@H](C1)n1nc(Nc2nc3ncc(Oc4ccnc(NC(C)=O)c4)c(Cl)c3n2C)cc1C(F)(F)C(F)(F)F

InChI Key InChIKey=SQTMUEPHSBERKL-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607992   

TargetTyrosine-protein kinase JAK2 [Y1007F,Y1008F](Human)
Ajax Therapeutics

US Patent
LigandPNGBDBM607992(US11691963, Example I-150)
Affinity DataKd: <10nMAssay Description:JAK2 (JH1domain-catalytic, Y1007F,Y1008F) kinase was expressed as N-terminal fusion to the DNA binding domain of NFkB in transiently transfected HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent