BDBM608058 US11691965, Compounds of formula (1)

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)-c2cnc(nc2)C2(F)COC2)[C@@H](C1)n1ccc(F)c1

InChI Key InChIKey=CJUWUQZGDOTRHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608058   

TargetHigh affinity nerve growth factor receptor(Human)
Zhangzhou Pien Tze Huang Pharmaceutical

US Patent
LigandPNGBDBM608058(US11691965, Compounds of formula (1))
Affinity DataIC50: 6.64nMAssay Description:In a 10 μL reaction system with a buffer of 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.01% Brij35, 0.1 mM sodium vanadate, 0.02 g/mL BSA, 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Zhangzhou Pien Tze Huang Pharmaceutical

US Patent
LigandPNGBDBM608058(US11691965, Compounds of formula (1))
Affinity DataIC50: 50nMAssay Description:The inhibitory activities of test compound against different isoforms of human cytochrome P450 isoenzymes were determined. Experimental Operation. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent