BDBM608073 (1-cyclopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(4-oxa-5-azaspiro[2.4]hept-5-en-6-yl)-3-azabicyclo[3.1.0]hex-3-yl]methanone::US11691968, Example 51::US20230271952, Example 51

SMILES O=C(c1cn(C2CC2)cn1)N1C[C@@H]2[C@H](C1)[C@H]2C1=NOC2(CC2)C1

InChI Key InChIKey=QKJRBVBERXPPIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608073   

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 608073BDBM608073(US11691968, Example 51 | (1-cyclopropyl-1H-imidazo...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 608073BDBM608073(US11691968, Example 51 | (1-cyclopropyl-1H-imidazo...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent