BDBM608153 4-bromo-5-(((S)-1- (((R)-2-oxo-1-(1-(5- (trifluoromethyl)pyrim- idin-2-yl)piperidin- 4-yl)pyrrolidin-3- yl)oxy)propan-2- yl)amino)pyridazin- 3(2H)-one::US11691969, Example 32::US11691969, Example 46B

SMILES C[C@@H](CO[C@@H]1CCN(C2CCN(CC2)c2ncc(cn2)C(F)(F)F)C1=O)Nc1cn[nH]c(=O)c1Br

InChI Key InChIKey=SJIJSEFLLIUUCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608153   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM608153(US11691969, Example 32 | 4-bromo-5-(((S)-1- (((R)-...)
Affinity DataIC50: 100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM608153(US11691969, Example 32 | 4-bromo-5-(((S)-1- (((R)-...)
Affinity DataIC50: 100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent