BDBM608248 US11691981, Compound 12

SMILES NS(=O)(=O)c1ccc(Nc2cc(Oc3cc(nn3C3CCOCC3)C(F)(F)F)ccn2)cc1

InChI Key InChIKey=UYIIGZVGRINQHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608248   

TargetTGF-beta receptor type-1(Human)
Inventisbio

US Patent
LigandPNGBDBM608248(US11691981, Compound 12)
Affinity DataIC50: 28nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent