BDBM608360 (Z)-15-chloro-25-(difluoromethyl)-96-fluoro- 13,21,61-trimethyl-11H,21H,61H-10-oxa-4,8- dithia-1(4,1)-indola-2(4,3),6(3,5)-dipyrazola- 9(3,1)-naphthalenacyclotridecaphane-12- carboxylic acid::US11691989, Compound 18
SMILES Cc1c(C(O)=O)n2CCCOc3cc(SCc4cc(CSCc5nn(C)c(C(F)F)c5-c5c(Cl)ccc2c15)nn4C)cc1cc(F)ccc31
InChI Key InChIKey=KMZPLNMPSAFZJF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 608360
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)
US Patent
Ascentage Pharma (Suzhou)
US Patent
Affinity DataIC50: 15nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair