BDBM608493 (5P)-2-[(3aR,6aS)-3a- (aminomethyl)-octahydro- cyclopenta[c]pyrrol-2-yl]-6-amino-5- (2,3-dichlorophenyl)-pyrimidine-4- carboxamide::US11696916, Compound 98::US11696916, Compound 99

SMILES Cc1nc(N2C[C@H]3CCC[C@@]3(CN)C2)nc(C(N)=O)c1-c1cccc(Cl)c1Cl

InChI Key InChIKey=YLFHJDAZPHOZQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608493   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 608493BDBM608493(US11696916, Compound 98 | US11696916, Compound 99 ...)
Affinity DataIC50: 49nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 608493BDBM608493(US11696916, Compound 98 | US11696916, Compound 99 ...)
Affinity DataIC50: 3.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2023
Entry Details
US Patent