BDBM608952 US11702409, Example 48

SMILES Cc1c(c(nn1C1CC2(C1)CN(C2)C(=O)C=C)-c1ccc(CN2CCCC2=O)cc1)-c1c(Cl)c(C)cc2[nH]ncc12

InChI Key InChIKey=UYONZSRMJZWIRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608952   

TargetGTPase KRas [G12C](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM608952(US11702409, Example 48)
Affinity DataIC50:  49nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent