BDBM608960 US11702411, Compound 10::{3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-6-(7-chloro-2,3-dihydro-1-benzofuran-6-yl)pyrazin-2-yl}methanol.

SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(nc2CO)-c2ccc3CCOc3c2Cl)[C@@H]1N

InChI Key InChIKey=BWVRZDYXCIFXKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608960   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM608960({3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]...)
Affinity DataIC50: 275nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent