BDBM608996 US11702409, Example 71a::US11702409, Example 71b

SMILES Cc1c(C)n(nc1-c1ccc2nnccc2c1)C1CC2(C1)CN(C2)C(=O)OC(C)(C)C

InChI Key InChIKey=PDKJRVVBGGFDNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608996   

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandPNGBDBM608996(US11702409, Example 71a | US11702409, Example 71b)
Affinity DataIC50: 101nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Novartis

US Patent
LigandPNGBDBM608996(US11702409, Example 71a | US11702409, Example 71b)
Affinity DataIC50: 5.00E+3nMAssay Description:Assays were run using 384-well plates (781207/Greiner) in which one column was designated as the high signal (no inhibition) control, and contained D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent