BDBM609373 US11702416, Example 24B

SMILES COc1cc2NC(=O)[C@H](Oc2c(c1)-c1cn(C)c(=O)c2[nH]ccc12)c1ccc(F)cc1Cl

InChI Key InChIKey=NNJNYMIRXGUCJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 609373   

TargetBromodomain-containing protein 4 [349-460](Human)
Incyte

US Patent
LigandPNGBDBM609373(US11702416, Example 24B)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-167](Human)
Incyte

US Patent
LigandPNGBDBM609373(US11702416, Example 24B)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent