BDBM609417 BDBM609769::DOTA[Cu(II)]- Gly-HyBz-D-Ala- boroPro::US11707539, Compound 6487::US20240207292, Compound 6487

SMILES C[C@@H](NC(=O)c1ccc(NNC(=O)CNC(=O)CN2CCN3CCN(CC(O)=O)CCN(CC2)CC(=O)O[Cu]OC(=O)C3)cc1)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=ZSHQLDQVBNLVOQ-UHFFFAOYSA-L

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 609417   

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609417(DOTA[Cu(II)]- Gly-HyBz-D-Ala- boroPro | BDBM609769...)
Affinity DataIC50: 2.10nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609417(DOTA[Cu(II)]- Gly-HyBz-D-Ala- boroPro | BDBM609769...)
Affinity DataIC50: 2.10nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609417(DOTA[Cu(II)]- Gly-HyBz-D-Ala- boroPro | BDBM609769...)
Affinity DataIC50: 8.80nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609417(DOTA[Cu(II)]- Gly-HyBz-D-Ala- boroPro | BDBM609769...)
Affinity DataIC50: 8.80nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609417(DOTA[Cu(II)]- Gly-HyBz-D-Ala- boroPro | BDBM609769...)
Affinity DataIC50: 8.80nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609417(DOTA[Cu(II)]- Gly-HyBz-D-Ala- boroPro | BDBM609769...)
Affinity DataIC50: 8.80nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent