BDBM609618 US11702418, Example 12-102

SMILES CCN1CCN(CC1)c1cc2c(N[C@H](C)c3cccc(C(F)F)c3F)nnc(C)c2cn1

InChI Key InChIKey=AQWSBJNTSISMTR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609618   

TargetSon of sevenless homolog 1 [564-1049](Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM609618(US11702418, Example 12-102)
Affinity DataKi:  0.25nMAssay Description:Table 22: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and prevent a labeled tracer ligand from occupying ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent