BDBM609775 US11707539, Compound 6556LU::US20240207292, Compound 6556LU

SMILES C[C@@H](NC(=O)c1ccc(CNC(=O)CN2CCN3CCN4CCN(CC2)CC(=O)O[Lu](OC(=O)C3)OC(=O)C4)nc1)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=CIWYCGJKMQVNMP-UHFFFAOYSA-K

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 609775   

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609775(US11707539, Compound 6556LU | US20240207292, Compo...)
Affinity DataIC50: 2.90nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609775(US11707539, Compound 6556LU | US20240207292, Compo...)
Affinity DataIC50: 2.90nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandPNGBDBM609775(US11707539, Compound 6556LU | US20240207292, Compo...)
Affinity DataIC50: 895nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase(Human)
Tufts College

US Patent
LigandPNGBDBM609775(US11707539, Compound 6556LU | US20240207292, Compo...)
Affinity DataIC50: 895nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent