BDBM609784 US11707539, Compound 6591::US20240207292, Compound 6591

SMILES C[C@@H](NC(=O)c1ccc(CNC(=O)CCCNC(=O)CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2)cc1)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=DUDRYQVTKPGWCP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 609784   

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609784(US11707539, Compound 6591 | US20240207292, Compoun...)
Affinity DataIC50: 0.360nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609784(US11707539, Compound 6591 | US20240207292, Compoun...)
Affinity DataIC50: 0.360nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandPNGBDBM609784(US11707539, Compound 6591 | US20240207292, Compoun...)
Affinity DataIC50: 103nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase(Human)
Tufts College

US Patent
LigandPNGBDBM609784(US11707539, Compound 6591 | US20240207292, Compoun...)
Affinity DataIC50: 103nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent