BDBM609823 (1R,3S,5R)-2-(2- (3-acetyl-7- methyl-5-(2- methylpyrimidin- 5-yl)-1H- indazol-1- yl)acetyl)-N-(3- chloro-2- fluorobenzyl)-5- methyl-2- azabicyclo[3.1.0] hexane-3- carboxamide::US11708351, Compound 28

SMILES CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@]3(C)C[C@H]2C(=O)NCc2cccc(Cl)c2Br)c2c(C)cc(cc12)-c1cnc(C)nc1

InChI Key InChIKey=NQWXHFHDXNPYET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 609823   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM609823(US11708351, Compound 28 | (1R,3S,5R)-2-(2- (3-acet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent