BDBM609997 1-N'-(4-fluorophenyl)-1-N- (4-pyrido[3,4-d]pyrimidin- 4-yloxyphenyl)cyclopropane- 1,1-dicarboxamide::US11708367, Compound 85
SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ncnc4cnccc34)cc2)cc1
InChI Key InChIKey=BAGLRIYGLUAGSG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 609997
Affinity DataIC50: 550nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis
US Patent
Exelixis
US Patent
Affinity DataIC50: 550nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair