BDBM610487 2-(Cyclohex-1-en-1-yl)-N-(4-(2-methylmorpholino)pyridin-3-yl)imidazo[1,2-b]pyridazine-8-carboxamide::US10774086, Example 35

SMILES CC1CN(CCO1)c1ccncc1NC(=O)c1ccnn2cc(nc12)C1=CCCCC1

InChI Key InChIKey=ZLWLGUFTYZQJRI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 610487   

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610487(US10774086, Example 35 | 2-(Cyclohex-1-en-1-yl)-N-...)
Affinity DataIC50: 1nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610487(US10774086, Example 35 | 2-(Cyclohex-1-en-1-yl)-N-...)
Affinity DataIC50: 1.60nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetMicrotubule-associated protein tau(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610487(US10774086, Example 35 | 2-(Cyclohex-1-en-1-yl)-N-...)
Affinity DataIC50: 160nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent