BDBM610488 N-(4-Morpholinopyridin-3-yl)-2-(pyridin-3-yl)imidazo[1,2-b]pyridazine-8-carboxamide::US10774086, Example 36

SMILES O=C(Nc1cnccc1N1CCOCC1)c1ccnn2cc(nc12)-c1cccnc1

InChI Key InChIKey=OQKSXFCBEUFFIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 610488   

TargetGlycogen synthase kinase-3 alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610488(US10774086, Example 36 | N-(4-Morpholinopyridin-3-...)
Affinity DataIC50: 0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610488(US10774086, Example 36 | N-(4-Morpholinopyridin-3-...)
Affinity DataIC50: 1.30nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent