BDBM610658 US11713327, Example ER-888286

SMILES C[C@@H]1CN(C[C@H](CN2CCN(CC2)c2ccncc2)O1)c1ccc(C#N)c2ncccc12

InChI Key InChIKey=OYIANONYDQUTCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 610658   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM610658(US11713327, Example ER-888286)
Affinity DataIC50: 1.30E+3nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent