BDBM610667 5-[(2S,6R)-2-[[4-[2-(2-hydroxyethyl)isoindolin-5-yl]piperazin-1-yl]methyl]-6-methyl-morpholin-4-yl]quinoline-8-carbonitrile::US11713327, Example 16

SMILES C[C@@H]1CN(C[C@H](CN2CCN(CC2)c2ccc3CN(CCO)Cc3c2)O1)c1ccc(C#N)c2ncccc12

InChI Key InChIKey=WNEFQTMZICJLDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 610667   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM610667(US11713327, Example 16 | 5-[(2S,6R)-2-[[4-[2-(2-hy...)
Affinity DataIC50: 2.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
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Date in BDB:
9/4/2023
Entry Details
US Patent