BDBM610676 5-[(2R,6S)-2-methyl-6-[[4-(5-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)piperazin-1-yl]methyl]morpholin-4-yl]quinoline-8-carbonitrile::US11713327, Example 41

SMILES CC1NCc2ncc(cc12)N1CCN(C[C@H]2CN(C[C@@H](C)O2)c2ccc(C#N)c3ncccc23)CC1

InChI Key InChIKey=LNLBHEKPIWHTQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 610676   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM610676(US11713327, Example 41 | 5-[(2R,6S)-2-methyl-6-[[4...)
Affinity DataIC50: 2.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
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Date in BDB:
9/4/2023
Entry Details
US Patent