BDBM611005 4-[5-(3-(R)-amino-piperidine-1- carbonyl)-2-(4-methoxy-phenyl)-1- methyl-1H-pyrrol-3-yl]-2-fluoro- benzonitrile::US10626103, Example 2

SMILES COc1ccc(cc1)-c1c(cc(C(=O)N2CCC[C@@H](N)C2)n1C)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=XWMPZHAOYSMCDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611005   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM611005(US10626103, Example 2 | 4-[5-(3-(R)-amino-piperidi...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
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Date in BDB:
9/8/2023
Entry Details
US Patent